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  • 标题:Molecular epidemiology, prenatal exposure and prevention of cancer
  • 本地全文:下载
  • 作者:Frederica Perera
  • 期刊名称:Environmental Health - a Global Access Science Source
  • 印刷版ISSN:1476-069X
  • 电子版ISSN:1476-069X
  • 出版年度:2011
  • 卷号:10
  • 期号:1
  • 页码:S5
  • DOI:10.1186/1476-069X-10-S1-S5
  • 语种:English
  • 出版社:BioMed Central
  • 摘要:Molecular Epidemiology was originally conceived as a preventive approach, providing a valuable tool for investigating risk factors for cancer in vulnerable populations. Biomarkers can be used as early indicators of risk for preventative purposes and risk assessment. The present contribution mainly refers to in utero exposures to carcinogens, since humans are especially vulnerable during fetal development. Environmental exposures in utero can increase risks for both childhood and adult cancers; their interactions with genetic and nutritional susceptibility factors may further increase risk. Thus, the early developmental period represents an important window for cancer prevention.
  • 关键词:Cord Blood ; Methylation Level ; Fetal Period ; Early Developmental Period ; Blood White Blood Cell
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