We commend the FluoroCouncil for phasing out long-chain poly- and perfluoroalkyl substance (PFAS) chemistry. However, members of the FluoroCouncil have been producing long-chain PFASs for decades while in possession of research showing adverse health effects in humans and animals. This model of chemical manufacturing needs to change. We recommend implementing the principles of green chemistry ( Anastas and Warner 1998 ) in chemical manufacturing to ensure safer and sustainable chemical products. The scientific consensus of the Madrid Statement authors and signatories is that the use of all PFASs is unsustainable, and can and should be greatly reduced and discontinued where feasible. Short-chain fluorinated alternatives were therefore intentionally included in the scope of the Madrid Statement.