The FluoroCouncil’s voluntary development of alternative chemistries is unprecedented and a model for the development and introduction of more sustainable chemistry worldwide. More than a decade ago, the FluoroCouncil member companies responded to concerns about long-chain poly- and perfluoroalkyl substances (PFASs) by working with regulators to voluntarily phase out those substances and develop alternatives with improved health and environmental profiles. The FluoroCouncil also works with regulators and other stakeholders to support a global transition away from long-chain PFASs. This effort stands as a historic collaboration by government and industry to foster sustainable development.