首页    期刊浏览 2024年11月24日 星期日
登录注册

文章基本信息

  • 标题:Comment on “ In Vitro Effects of Bisphenol A β-D-Glucuronide (BPA‑G) on Adipogenesis in Human and Murine Preadipocytes”
  • 本地全文:下载
  • 作者:Véronique Gayrard ; Glenn Gauderat ; Marlène Z. Lacroix
  • 期刊名称:Environmental Health Perspectives
  • 印刷版ISSN:0091-6765
  • 电子版ISSN:1552-9924
  • 出版年度:2015
  • 卷号:123
  • 期号:12
  • 页码:A289
  • DOI:10.1289/ehp.1510315
  • 出版社:OCR Subscription Services Inc
  • 摘要:

    Boucher et al. reported that treatment of 3T3L1 preadipocytes with 10 μM bisphenol A β-D-glucuronide (BPA-G) induced a significant increase in lipid accumulation, in mRNA expression of the adipogenic markers sterol regulatory element binding factor 1 ( SREBF1 ) and lipoprotein lipase ( LPL ), and in protein levels of LPL, aP2, and adipsin. They concluded that their study was the first to show that BPA-G induced adipocyte differentiation and was not simply an inactive metabolite.

国家哲学社会科学文献中心版权所有