期刊名称：International Journal of Innovative Research in Science, Engineering and Technology
印刷版ISSN：2347-6710
电子版ISSN：2319-8753
出版年度：2015
卷号：4
期号：1
页码：18944
DOI：10.15680/IJIRSET.2015.0401070
出版社：S&S Publications
摘要：Hydrazones derivatives of carbonyl compounds constitute an important class of biologically activecompounds. Metal complexes of Schiff bases represent an important class of coordination compounds. Schiffs basecontaining hetero donar atom continue to provide the interesting facts in the fields of coordination chemistry.Literature studies on hydrazones have shown that these derivatives possess a wide variety of biologicalactivities such as anti-tumour, anti-bacterial, anti-viral, anti-hypertensive, analgesic etc. Complexes of Co(II), Ni(II)and Zu(II) with schiff base [LH2] derived from 2- hydroy – 5 – Bromo -3- Nitro acetophenone and isonictonoylhydrazide have been synthesized and characterized on the basis of molar conductance magnetic properties, elementalanalysis, infrared, 1H NMR, electronic spectra and thermo gravimetric analysis. The schiff base acts as mono basic bidentateligand commonly co-ordinates through the oxygen atom of the deprotonated phenolic group and the nitrogenatom of azomethine group, which is confirmed by IR spectral data. Thermal analysis indicates the coordinated andlattice water molecules in the complexes which are also I.R. spectral data.
关键词：Schifft bare; Magnetic Susceptibility; Biological activates
