期刊名称：International Journal of Innovative Research in Science, Engineering and Technology
印刷版ISSN：2347-6710
电子版ISSN：2319-8753
出版年度：2015
卷号：4
期号：5
页码：3525
DOI：10.15680/IJIRSET.2015.0405108
出版社：S&S Publications
摘要：Compound 2-(5-fluoro-2-methyl-1H-inden-3-yl) acetohydrazide was reacted with various substitutedaldehydes at elevated temperature in methanol to yield substituted N-benzylidene-2-(2-methyl-1H-inden-3-yl)acetohydrazide as sole product. It is also observed that reaction went to completion during 8-10 hrs at reflux conditionwithout adding any acid or base catalyst. The reaction condition found general for all the substituted benzaldehyde.These derivatives are found more than 80% in yield. These new compounds are studied for the antimicrobial activity.
