期刊名称:International Journal of Innovative Research in Science, Engineering and Technology
印刷版ISSN:2347-6710
电子版ISSN:2319-8753
出版年度:2015
卷号:4
期号:5
页码:3525
DOI:10.15680/IJIRSET.2015.0405108
出版社:S&S Publications
摘要:Compound 2-(5-fluoro-2-methyl-1H-inden-3-yl) acetohydrazide was reacted with various substitutedaldehydes at elevated temperature in methanol to yield substituted N-benzylidene-2-(2-methyl-1H-inden-3-yl)acetohydrazide as sole product. It is also observed that reaction went to completion during 8-10 hrs at reflux conditionwithout adding any acid or base catalyst. The reaction condition found general for all the substituted benzaldehyde.These derivatives are found more than 80% in yield. These new compounds are studied for the antimicrobial activity.