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  • 标题:SYNTHESIS, STRUCTURE AND BIOLOGICAL ACTIVITY OF N(4)-ALLYL-3-THIOSEMI-CARBAZONES AND THEIR COORDINATION COMPOUNDS WITH SOME 3D METALS
  • 作者:Vasilii GRAUR
  • 期刊名称:Studia Universitatis Moldaviae: Stiinte Exacte si Economice
  • 印刷版ISSN:1857-2073
  • 电子版ISSN:2345-1033
  • 出版年度:2015
  • 期号:6(86)
  • 页码:130-141
  • 出版社:Moldova State University
  • 摘要:The paper presents a review of different N(4)-allyl-3-thiosemicarbazones and their coordination compounds describedin literature. N(4)-allyl-3-thiosemicarbazide can form corresponding thiosemicarbazones with aliphatic, aromatic andheteroaromatic carbonyl compounds. In the presence of transitional metal ions they can form coordination compoundsof different structures. Both coordination compounds and proligands manifest antitumor, antibacterial, antiviral, andantimalarial activities. Copper(II) coordination compounds with these ligands manifest better antitumor activity thancorresponding proligands
  • 关键词:N(4)-allyl-3-thiosemicarbazone; complexes; biological activity
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