期刊名称:Studia Universitatis Moldaviae: Stiinte Exacte si Economice
印刷版ISSN:1857-2073
电子版ISSN:2345-1033
出版年度:2014
期号:6(76)
页码:119-123
出版社:Moldova State University
摘要:The paper presents the synthesis of the ligand 5-nitrofuran-2-carbaldehyde N(4)-allyl-3-thiosemicarbazone (HL) and eight coordination compounds of copper(II) and nickel(II) with this ligand. The structure of thiosemicarbazone HL was studied using 1H and 13С NMR spectroscopy. For the synthesized compounds their antimicrobial and antifungal activity was studied on a series of standard strains. For HL and Cu(HL)2(NO3)2 the antitumor activity towards human leukemia HL-60 cells was estimated. It was established that coordination compounds manifest better activity than free ligand