摘要:The article subject is the conceptual nuclear of the positive-dialectical epistemology programs. The author demonstrates its possibilities and advanced from the trancscendentalism, positivism and postpositivism epistemological conceptions. He formulates the seven main sentences of positive-dialectical conception: 1) nesessity the system approach for solution the problem of demarcation scientific knowledge; 2) the social nature of scientific investigation; 3) the plural and contradiction character of the system scientific knowledge; 4) the methodological pluralism in the science as on the scientific areal and disciplines as on the levels of scientific knowledge; 5) the double determination of scientific knowledge: object and sociocultural; 6) the dynamic of the scientific exchanges includes continuality and discretcions, generalisation and negation of old knowledge, internal and external factors; 7) the philosophical reflection on the scientific investigation and its dynamics is the necessity point of scientific progress.