出版社:State Institution “O.M. MARZEYEV INSTITUTE FOR PUBLIC HEALTH OF THE NAMS OF UKRAINE"
摘要:During the experiment on the rats, the effect of 10 nm, 30 nm, 400 nm lead particles on fatty acid (FA) composition of liver lipids was made. It was found, that the most evident changes of liver lipid comlex occur within 6 weeks with the particle size of 400 nm, while the most marked damage of liver lipids levels is made by 10 nm and 30 nm nanoparticles over a period of a 12-week activity of the studied factor. Hereby our studies suggest that changes of FA in liver lipid composition depend on the size of nanoparticles and duration of the effect. To identify the clearest patterns of dependence on "dose – time - effect", it is necessary to continue and expand started research.