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  • 标题:The role of adipokines in HIV lipodystrophy
  • 本地全文:下载
  • 作者:Gordana Dragović
  • 期刊名称:Germs
  • 印刷版ISSN:2248-2997
  • 出版年度:2015
  • 卷号:5
  • 期号:3
  • 页码:64
  • DOI:10.11599/germs.2015.1072
  • 出版社:European HIV/AIDS and Infectious Diseases Academy
  • 摘要:Changes in body fat distribution are frequent findings in HIV/AIDS patients, with onset shortly after initiation of combination antiretroviral therapy (cART). Lipoatrophy (loss of peripheral subcutaneous fat from the face, arms, legs and buttocks, coupled with pronounced blood vessels in the arms and legs), can occur alone or in combination with lipohypertrophy (fat accumulation on the dorsocervical and abdominal regions). These changes are associated with diabetes and insulin resistance, metabolic abnormalities and increased risk of cardiovascular diseases.
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