摘要：In this study, the aerial parts of M. x piperita were collected from Uşak province, Turkey, and the antimicrobial and antibiofilm activities were investigated. Essential oil from the aerial parts of this plant was obtained with the hydrodistillation method. In vitro antimicrobial activities of the essential oil on various antibiotic resistant bacteria; Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Pseudomonas fluorescens, and the yeast Candida albicans were tested by disc diffusion and microplate dilution methods. The effect of different concentrations of the essential oils on biofilm-forming ability of the test microorganisms were determined by microplate biofilm method. The essential oils of M. x piperita had antimicrobial activity against the tested bacteria, except for P. aeruginosa MU 187, and the inhibition zones were between 10-15 mm. As a result of the MIC test, the essential oil was most effective against S.aureus MU 38 and 1 μg/ml concentration of essential oil was found to inhibit this strain. The essential oil of M. x piperita was found to have different proportions of antibiofilm activity against all Gram- positive test strains.To our knowledge, this is the first study of the antibiofilm activity of the essential oil of M. x piperita collected from Turkey. The results showed that the essential oil can be used as an antibiofilm agent against the biofilm ability strains. This activity is an important topic in the medical field as well as in the food industry
关键词：Mentha x piperita; Lamiaceae; essential oil; antimicrobial activity; antibiofilm activity
