期刊名称：Egyptian Journal of Pediatric Allergy and Immunology
印刷版ISSN：1687-1642
电子版ISSN：2314-8934
出版年度：2006
卷号：4
期号：1
页码：3-13
出版社：Egyptian Society of Pediatric Allergy and Immunology
摘要：Although CVID is a rare condition, it is probably the most common symptomatic primary immunodeficiency syndrome encountered by the allergy/immunology and pulmonary specialist 1. Its prevalence ranges from 1:25.000 among Caucasians to 1:100.000 in the Japanese population, and affects men and women equally3.The majority of patients exhibit symptoms either in childhood or late-adolescence and present mainly with sinopulmonary infections4. However, in some patients, the disease does not become clinically apparent until the second or third decade of life, frequently with some delay between initial onset of recurrent infections and the establishment of the diagnosis5.
