期刊名称：Egyptian Journal of Pediatric Allergy and Immunology
印刷版ISSN：1687-1642
电子版ISSN：2314-8934
出版年度：2012
卷号：10
期号：1
页码：45-48
出版社：Egyptian Society of Pediatric Allergy and Immunology
摘要：Cardiopulmonary involvement is one of the important manifestations ofsystemic lupus erythematosus (SLE) that tends to be more common in adultsthan children with SLE. SLE-related cardiopulmonary affection ranges fromsubclinical to life threatening condition. Although increased left ventricularmass and interstitial lung disease have been reported in association withSLE, the reversibility of such conditions with treatment of SLE was notsufficiently reported. Herein, we describe a female adolescent with SLE andlupus nephritis class III who presented as well with moderate dyspnea,tachycardia in absence of heart failure and hypertension. She had alsoproductive cough of whitish sputum, no fever and both sputum and bloodcultures were negative. Her echocardiography revealed left ventricular wallhypertrophy with preserved systolic function, electrocardiogram showedsinus tachycardia. Her pulmonary function tests revealed mild restrictivepattern and high resolution computed tomography revealed veiling of bothlungs with increased attenuation and interstitial nodules with bilateral mildpleural effusion. She received full dose prednisone and intravenous monthlycyclophosphamide in addition to intravenous pulsed methylprednislone. Shegradually improved with complete resolution of her cardiopulmonarydisease and significant reduction of her proteinuria. In conclusion,cardiopulmonary involvement in relation to SLE could be reversible withadequate treatment leaving no residual damage.
关键词：SLE; left ventricular hypertrophy; interstitial lung disease
