期刊名称：Egyptian Journal of Pediatric Allergy and Immunology
印刷版ISSN：1687-1642
电子版ISSN：2314-8934
出版年度：2013
卷号：11
期号：1
页码：23-28
出版社：Egyptian Society of Pediatric Allergy and Immunology
摘要：There are no published data on fish allergy in Egypt.Objective: We sought to screen for the frequency of fish sensitization in agroup of atopic Egyptian infants and children in relation to theirdemographic and phenotypic data.Methods: We consecutively enrolled 87 allergic children; 1-15 years old(median 5.0 yr). The study measurements included clinical evaluation forthe site and duration of allergy, possible precipitating factors, and familyhistory of allergy as well as skin prick testing with a commercial fishextract, and serum fish specific and total IgE estimation.Results: Twelve subjects (13.8%) were sensitized to fish as evidenced bypositive skin prick test (SPT) results; five (41.7%) of them gave a historysuggestive of fish allergy compared to two (2.7%) of the non-sensitizedchildren (p=0.00). The SPT results did not vary significantly with age,gender, family history of atopy, or serum total or fish specific IgE(SpIgE).Conclusion: Fish sensitization does not seem to be rare in atopicchildren in Egypt. It can be associated with any clinical form of allergyand the causal relationship needs meticulous evaluation. Wider scalepopulation-based studies are needed to assess the prevalence of fishallergy and its clinical correlates in our country.
关键词：fish allergy; sensitization; skin prick test; specific IgE;children; Egypt
