期刊名称：Egyptian Journal of Pediatric Allergy and Immunology
印刷版ISSN：1687-1642
电子版ISSN：2314-8934
出版年度：2013
卷号：11
期号：2
页码：63-67
出版社：Egyptian Society of Pediatric Allergy and Immunology
摘要：There are no published data on the prevalence of sesameallergy/sensitization in Egypt. Objective: In this pilot study, we thought toestimate the frequency of sesame seed sensitization in a group of atopicEgyptian infants and children. Methods: We consecutively enrolled 90patients with physician diagnosed allergic disease. The study measurementsincluded clinical evaluation for the site and duration of allergy, historysuggestive of sesame seed allergy, and family history of allergy, as well asskin prick testing (SPT) using a commercial sesame extract, and serumsesame specific IgE (SpIgE) estimation. Results: None of the studiedpatients reported symptoms suggestive of sesame seed allergy. Nevertheless,two children (2.2%) showed positive SPT response to sesame (whealdiameter ≥ 3 mm above the negative control). Only one of them had a whealdiameter which exceeded that of the histamine control. The serum sesameSpIgE exceeded 0.35 IU/ml in all subjects [range = 0.35 - 3.0 IU/ml; median(IQR) = 0.9 (0.6) IU/ml]. Serum sesame SpIgE was significantly increasedin patients with history of recurrent urticaria (p=0.03). Conclusion: Sesameseed sensitization is not uncommon in atopic Egyptian children. It can beassociated with any clinical form of allergy and the causal relationshipneeds meticulous evaluation. Wider scale population-based studies areneeded to assess the prevalence of sesame allergy and its clinical correlatesin our country.
