期刊名称：Egyptian Journal of Pediatric Allergy and Immunology
印刷版ISSN：1687-1642
电子版ISSN：2314-8934
出版年度：2014
卷号：12
期号：1
页码：13-20
出版社：Egyptian Society of Pediatric Allergy and Immunology
摘要：Egg allergy is potentially life-threatening. The prevalence of egg allergy in Egypt is still unclear. This study is to evaluate the frequency of egg hypersensitivity in a group of Egyptian atopic children.Methods:Eighty allergic children were enrolled, each is subjected to clinical evaluation, skin prick testing (SPT) using a commercial egg white extract, and serum egg white specific IgE (SpIgE) estimation. Six patients with suspected egg allergy consent to perform open oral egg challenge.Results:Twenty-eight patients had history of exacerbation of their allergic diseases upon exposure to egg white, of these patients, 8had negative SPT and serum egg white SpIgE.SPT was positive in 25(31.2%) patients, of these patients, 3(4%) were +3, 22(28%) were +2, of whom 5patients tolerate eggs without adverse effects. Serum egg white SpIgE was positive in 19(24%) patients with a mean of 0.81IU/ml (range: 0.35-4.52IU/ML). Egg white allergy based on positive history, positive SPTand/or egg white SpIgE was detected in 23(28.8%) patients. Open oral egg challenge was positive in one patient with positive history but negative tests giving an overall frequency of egg allergy of 30% (n=24).While egg white SpIgE did not correlate withthe ages, positive SPT was significantly more frequent among younger patients (t= 1.7, p=0.02). Egg sensitization and allergy did not affect the severity of asthma (p > 0.05).Conclusion:Although positive SPT/ serum specific IgE to eggs are good tools for diagnosis, oral food challenge remains the gold standard in suspected cases. Further wide-scale studies are needed to outline the real prevalence of egg allergy in Egypt
关键词：Egg allergy ; – ; ; children ; – ; ; skin prick test
