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  • 标题:Development of immunization trials against Acinetobacter baumannii
  • 作者:Tarek A. Ahmad ; Dina M. Tawfik ; Salah A. Sheweita
  • 期刊名称:Trials in Vaccinology
  • 电子版ISSN:1879-4378
  • 出版年度:2016
  • 卷号:5
  • 页码:53-60
  • DOI:10.1016/j.trivac.2016.03.001
  • 出版社:Elsevier
  • 摘要:Acinetobacter baumannii has recently crossed all lines once considered harmless, pushing its way as a nosocomial pathogen. It had acquired resistance to almost all available chemotherapies and mainly targets intensive care residents; causing pneumonia and major outbreaks with high mortality rates. This urged the need for preventive methods, which include infection control, non-specific immune-therapy, passive, and active immunization in order to offer vulnerable immune-compromised patients a flare in the dark. Several attempts were done for constructing effective vaccines with promising results. These are precisely classified, documented, and discussed in this up-to-date review.
  • 关键词:Nosocomial infection ; Acinetobacter baumannii ; Vaccine ; Immunotherapy
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