The hamate fracture is very rare injury in carpal bone fractures. The mechanism of fracture may be attributed to indirect trauma with clenched fist. We have experienced a case of fracture of the body of the hamate bone. It was treated with open reduction and OA miniscrew fixation and plaster immobilization for four weeks and physical therapy. At 21 months follow-up, the result was satisfactory without traumatic arthritis, nonunion, ulnar nerve palsy, and limitation of motion. A case of fracture of the body of the hamate bone is reported with review of literatures.