PURPOSE: The femoral unicondylar fractures occur less frequently than the supracondylar or intercondylar femoral fractures. We document the problems and results in the treatment of these fractures. MATERIALS AND METHODS: Eleven patients with minimal follow-up peroid of 12 months were included. In the methods of treatment, the operation with by closed or open reduction and internal fixation with screws was used for 7 cases, the conservative treatment for 4 cases. The therapeutic outcomes were rated by the Lysholm knee scoring scale. RESULTS: The concomitant injuries including neurovascular, collateral or cruciate ligaments and capsular structures of knee to ipsilateral extremity were frequent events. The therapeutic outcomes were significantly affected by associated injuries. The only 5 cases had satisfactory result by the Lysholm knee scoring scale. CONCLUSION: These injuries have been considered to be the result of high-energy trauma on flexed knee. The open reduction and internal screw fixation of the femoral unicondylar fractures are necessary for good results because those are unstable and easily displaced. The associated disruption of the cruciate ligament was frequently associated injury and, significantly affected to the therapeutic outcome.