Some foreign reports state that 60~80% of patients hospitalized with cancer suffer with pain. The cancer patients usua1ly have exacerbation of pain corresponding to the progre-ssion of the disease. The management of cancer relate? pain includes the followings : 1) Attacking the pathologr causin? the pain 2) Raising the pain thresheld 3) Modulating the pain pathway 4) Interrupting the pain pathwazy. The most important aspect in management of cancer related pain is stepladder approach to ana17esic tailoring. The development of toleranoe with prolonged uke of analgesics requires increasing dose of analgesics. Not only does the increased dose of analgesics affect analgesia but also increases side effectg increases. Chemical nerve blocks and neurosurgical ablation can be used in management of terminal cancer patients. With the development of multimodal approaches to caring cancer patients one shruld be cautious in Using ablative therapy. ln our pain clinics, 123 cancer related pain patients have been managed with non-narc-odic analgesics, narcotic analgesics, celiac plexus block, and intrathecal phenol block, imp-lant ation of permanent epidural catheter.