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  • 标题:Safety and Efficacy of Epinephrine and Morphine Added to Bupivacaine for Lumbar Epidural Anesthesia in Obstetrics
  • 作者:Jo, Yung Il ; Park, Tae In ; Park, Chul Hong
  • 期刊名称:Korean Journal of Anesthesiology
  • 印刷版ISSN:2005-6419
  • 出版年度:1987
  • 卷号:20
  • 期号:2
  • 页码:177-181
  • DOI:10.4097/kjae.1987.20.2.177
  • 语种:Korean
  • 出版社:The Korean Society of Anesthesiologists,
  • 摘要:

    The effects of epidural bupivacaine with and without epinephrine and morphine on mat-ernal blood pressure, newborn Apgar scores, and duration of analgesia were compared in 40 parturients during Cesarean section and post operative periods. Patients in group 1(n= 16) received 0.5% bupivacaine 27cc and group 2(n=10) recelved bupivacaine with epinephrine, group 3 (n= 10) received bupivacaine with morphine 3mg, and those in group 4(n= 10) received bupivacaine with epinephrine and morphine 3mg. Maternal hypotension occured less frequently in group 2 than in group 1 (p<0.001). Apgar scores were equally good (more than 8) all four groups. Duration of analgesia was longer in group 2(199.50±70.73min) than in group 1(133.50±50. 11min) but significantly longer in group 3(471.50±174.90) and in group 4(684.00±276. 92min) . It is concluded that adding epinephrine and morphine to bupivacaine during epidural anesthesia in the normal parturient has no adverse effects on either mother or neonate; and that it significantly prolongs the duration of analgesia and decreases the incidence of maternal hypotension.

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