When the endotracheal tube is removed, blood pressure elevates and heart rate increases. In order to evaluate the hemodynamic changes after removal of a new developed device-laryngeal mask airway, we measured the change of the systolic & diastolic blood pressure and heart rate of 120 patients undergoing general anesthesia. The results were elevation of blood pressure and heart rate after extubation or removal on both groups immediately. But the degree of changes were 18.7±1.6% in the endotracheal tube groups and 12.3±1.4% in the laryngeal mask airway groups in systolic blood pressure respectively. Therefore the degree of changes of the laryngeal mask airway groups was significantly small (p<0.05). The comparison of the change of diastolic blood pressure was not significant. The degree of the change in heart rate was 19.6±2.8% in the endotracheal tube groups and 9.2±2.2% in the laryngeal mask airway groups. Therefore the degree of the ehange in blood pressure and heart rate of the laryngeal mask airway groups was significantly small (p<0.05).