The Department. of Anesthesiology of Hanyang University had a case of operation for pheo- chromocytoma. For the operation of pheochromocytoma, used to prazosin for preoperative treatment of hypertension and used to enflurane as inhalational anesthetic, treated with sodium nitroprusside for severe elevation of blood pressure during operation, used to vecuronium for neuromuscular blocker. Also we tried to get the knowledge about the variation of catecholamine concentration in blood through operation. As we used to the other drugs with adequate amount of fluid without any other complication in this operation we reported here with other references and our experience of a case of operation for remove of pheochromocytoma.