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文章基本信息

  • 标题:Clinical Evaluation of Atracurium for Endotracheal Intubation
  • 作者:Woo, Nam Sick ; Lee, Ye Chul
  • 期刊名称:Korean Journal of Anesthesiology
  • 印刷版ISSN:2005-6419
  • 出版年度:1989
  • 卷号:22
  • 期号:3
  • 页码:409-412
  • DOI:10.4097/kjae.1989.22.3.409
  • 语种:Korean
  • 出版社:The Korean Society of Anesthesiologists,
  • 摘要:

    The usefulness of nondepolarizing muscle relaxants for intubation is limited by a relatively slow onset of neuromuscular block compared to that achived with succinylcholine. But, authors have reported that larger doses of nondepolarizing muscle relaxants produce a more rapid onset of maximal neuromuscular block and conditions conductive to endotracheal intubation and recent reports support the use of the "priming principle in the clinical practice of anesthesiology. This phenomenon may apply to all nondepolarizing relaxants: it is reported to facilitated neuromuscular blockade and tracheal intubation when used with atracurium, vecurouium, alcuronium or pancuronium. In this study, administering a small subclinical dose of atracurium (75ug/kg) Smin. prior to the remainder of an intubating doae of atracurium (250ug/kg) had no different on grade of block for intubation compared to single IV bolus of atracurium (500ug/kg).

  • 关键词:Neuromuscular Relaxants-atracurium; Endotracheal Intubation-priming principle
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