期刊名称：International Journal of Software Engineering and Its Applications
印刷版ISSN：1738-9984
出版年度：2016
卷号：10
期号：1
页码：15-26
DOI：10.14257/ijseia.2016.10.1.02
出版社：SERSC
摘要：This paper presents a method of conversion of color image of histopathological slides to grayscale as a preprocessing step for image segmentation. The method utilizes characteristics of these images to reduce the amount of information lost during the conversion. It is a global mapping scheme and the same color does not map to two different grayscale values. Color information is added to the brightness information to reduce information loss and the weights for the added color are dependent on the distribution of the pixels in a particular image. The method was tested on a large set of histopathological slide images and convincing results were obtained some of which has been published in this paper.
关键词：Histopathological slides; Grayscaling; CIE Lab colorspace; Luminance and ; Hue
