Cereals are being utilized as the staple food in most parts of the world. The food products prepared from the cereals are the essential part of the daily diet worldwide. Several studies indicate that the consumption of whole grain food products reduces the risk of wide spread chronic diseases. Wheat and rye are the members of Gramineae family and are used to cure some common ailments. These are rich in different nutrients and their bran is the excellent source of dietary fiber. They also provide substances such as the lignans, alkyresorcinol, phytosterols, phenolic acids, folates, tocopherols and tocotrienols. The biologically active components found in wheat and rye have several health benefits. These not only help to prevent digestive disorders and cancer but also provide protection against cardiovascular diseases and help in reduction of the different health problems such as constipation, obesity, diabetes and appendicitis.