The nutritional composition and economic benefits of two perennial crops Tetracarpedium conophorum (African walnut) and Irvingia gabonensis (African bush mango) were studied. The results showed that both samples had high percentage oil yield with I.gabonensis having more yield. I. gabonensis have more protein content, 9.02% compare to 3.17% of T. conophorum. They both have high percentage of carbohydrate, T. conophorum 51.03% compared to I. gabonensis 12.74%. The fatty acid composition of the I.gabonensis are mainly saturated fatty acid as compared to high percentage of unsaturated fatty acid in T. conophorum, and this implies that, T. conophorum can provide the body with essential fatty acid. In conclusion, both samples have good nutritive values and can also be of economic importance in soap making, oil and domestic food industries given their being perennial plants with guaranteed availability during seasons. In addition, the consumption of I. gabonensis can be substituted for T.conophorum because of its high percentage of saturated fatty acid in order to avoid health risks associated with too much consumption of saturated fatty acid.