摘要:This study was done to determine and evaluate the level of lipid peroxidation product and vitamins C and E in rheumatoid arthritis. 150 rheumatoid arthritis and 150 healthy subjects between the ages of 45-60years attending General Hospital Owerri were selected in this study. Fasting veinous blood was collected and was used for the estimation of lipid peroxidation product and vitamins C and E in rheumatoid arthritis. The result obtained showed that the level of lipid peroxidation product was significantly increased in rheumatoid arthritis when compared with the healthy control (P<0.05). On the other hand, the level of vitamins C and E were significantly reduced in rheumatoid arthritis when compared with the control (P<0.05). This observation showed that rheumatoid arthritis is prone to oxidative stress and the antioxidant vitamins are excessively used to scavenge free radicals. Hence, the levels of antioxidant vitamins are depleted
关键词:Antioxidant Vitamin C and E; Lipid Peroxidation; Rheumatoid Arthritis