摘要：4-Thiazolidinone has been prepared by the reaction of various Schiff bases (2,4) withthioglycolic acid in presence of anhydrous zinc chloride and solvent N,N-Dimethyl formamide to affordednovel componds of 4-thiazolidinone (3,5), The intermediate Schiff base were synthesized by thecondensation of 2,6-bis (m-chloro phenyl) 3,5-dimethyl-4-piperidone-4 (1) with 4,4'-diaminodiphenylsulphone (2) and 4-methylbenzene -1,3-diamine (4) The structure of all the synthesizedcompounds were elucidated by spectral (IR,1H-NMR,13C-NMR and Mass) and elemental (C,H,N) analysis.All the synthesized compounds have been screened for their antibacterial properties against variousbacterial strains in order to obtain chemotherapeutic properties and these compounds were tested todetermine their ability to inhibit corrosion of mild steel in 1 mol.l-1H2SO4 and measured by polarizationmeasurements. The studies revealed that nitrogen, the piperidine moiety, the phenyl ring, 4-thiazolidinone assist largely in corrosion control
