摘要:Staphylococcus aureus is a recognized human pathogen responsible for a great variety of pyogenic infection in man and animals. The aim of this study was to determine prevalence and antibiotic resistance pattern of Staphylococcus aureus isolated from skin of different professional groups. A total of forty (40) Staphylococcus aureus strains were isolated from skin of 4 professional groups: teachers, students, patient samples, and nurses. The strains were identified on the basis of biochemical tests to be Staphylococcus aureus. Agar disc diffusion test was performed to determine antibiotic susceptibility pattern of the isolates. Nurses and Patient samples exhibited a higher resistance rate than normal microflora isolates from teachers and students. One of the nurse samples was resistant to at least 9 antibiotics, and one of the patient samples was resistant to at least 8 antibiotics. Over 62.5% of the strains are resistant to 5 or more of the antibiotics tested. 100% of the isolates tested were susceptible to vancomycin, where 95.0%, 92.5% and 73.5% of the isolates tested were susceptible to bacitracin, ciprofloxacin and cefaclor respectively.