摘要:The inflammation process exerts a critical role in the pathophysiology of insulin resistance (IR) as the reason behind of the chronic disease including diabetes, cancer and cardiovscular diseases. In this regard recently described n-3 fattyacids-derived mediators such as resolvins series D and E (from DHA (docosahexaenoic acid) and EPA ( eicosapentaenoic acid), respectively) and protectins affect the inflammatory process and immune system through blocking the inflammatory mediator production in result of diminishing the accumulation of leukocytes at the site of inflammation. In this article, we aimed to discuss resolvin as a marker which involves in inflammation and insulin resistance.