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  • 标题:RESOLVINS: LIPID MEDIATORS IN RELATION WITH INFLAMMATION AND INSULIN RESISTANCE
  • 本地全文:下载
  • 作者:Nava Morshedzadeh ; Fateme Zabetian-Targhi ; Maryam Mahmoudi
  • 期刊名称:Journal of Current Research in Science
  • 印刷版ISSN:2322-5009
  • 出版年度:2014
  • 卷号:2
  • 期号:6
  • 页码:902-908
  • 出版社:Islamic press
  • 摘要:The inflammation process exerts a critical role in the pathophysiology of insulin resistance (IR) as the reason behind of the chronic disease including diabetes, cancer and cardiovscular diseases. In this regard recently described n-3 fattyacids-derived mediators such as resolvins series D and E (from DHA (docosahexaenoic acid) and EPA ( eicosapentaenoic acid), respectively) and protectins affect the inflammatory process and immune system through blocking the inflammatory mediator production in result of diminishing the accumulation of leukocytes at the site of inflammation. In this article, we aimed to discuss resolvin as a marker which involves in inflammation and insulin resistance.
  • 关键词:Insulin resistance; lipid mediators; Resolvin; Inflammation disease
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