摘要：Many different types of adverse events occur after vaccination. The any reports serious adverse events involving life-threatening conditions, hospitalization, permanent disability, or death, which may or may not have been caused by a vaccine. The aim of this study was to determine the incidence of Vaccine Adverse Event of vaccination in children and infant hospitalized in Qom Children Hospital. In a retrospective study, all hospitalized children suspected to adverse vaccine effects were studied in Qom Children Hospital between October 2007 - October 2013. A specific questionnaire, including vaccine recipient profile, type of vaccine, and 18 adverse reactions were completed after hospitalization. The patients with underline disorders and coincidence of disease were excluded. This study included 145 children who were clinically suspected with Vaccine Adverse Event. The most common adverse reactions were: fever (66.9%), febrile seizures (54%), swelling at the vaccination site (3.4%), Vomiting (54.5%), cellulites & abscess at injected site (13.1%). Restlessness (7.6%),Weakness(4.1%). The most cause of hospitalization was adverse reaction of MMR vaccine. PCR of polio virus was positive in stool of patient who was presented with paralysis. Febrile seizures were most prevalent in the age of 18 months, respectively, with significant difference (P˂0.01) and (P˂0.001).In general, routine immunization program against nine common infectious Diseases have low side effects which generally are mild and transient and most disappear even without medical treatment. A careful follow-up report on the effects of the immunization program is essential. Use of acellular pertussis vaccine should be considered for decreasing the rate of post DTP side effects.
关键词：Vaccination; Vaccine Adverse Event; Children;Infant; immunization program
