摘要:Nurses constitute the largest professional group in the health care sector, and they are subjected to high level of occupational stress. Work-related stress is likely have a profound effect on depression, anxiety and job satisfaction among nurses. By measuring the job stress among nurses and its adverse effects, this research aims at providing an appropriate managerial solution to reduce this problem. This study is descriptive and analytical; it was temporarily performed in Iran. The participants were 250 persons whom were selected and investigated among nurses. This research was tested by four questionnaires. OSIPOW for stress, Ruth and Berry field’s for Job satisfaction, Beck Anxiety (BAI) and Depression Inventory (BDI) and was analyzed by SPSS 22 statistical software. The results showed that a significant proportion of nurses suffered from stress. 68% of these nurses reported medium-to-high degrees of stress. As well as, 35.6% of nurses have stated their satisfaction with job as very low and only 7.2% of them have been completely satisfied with their job. 18.8% of nurses were fairly depressed and 31.2% of them stated that medium to sever anxiety. The results indicate that work-related stress was negatively associated with depression, job satisfaction and anxiety. These findings suggest that there is a need to focus on knowledge and development of preventive strategies against stress, as well as rehabilitation for nurses with psychological distress in the work place