摘要：Cells continuously produce free radicals and reactive oxygen species (ROS) as part of metabolic processes. Exercise can induce an imbalance between ROS and antioxidants, which is referred to as oxidative stress. Acute bout of resistance exercise (RE) induces activation of several distinct systems of radicals generation, but the effects of different RE loading on oxidative stress response is not clear. Therefore, the purpose of this study was to examine the influence of cluster vs. traditional sets of RE on oxidative DNA damage, lipid peroxidation and uric acid response in athletes. To elicit blood oxidative stress, 12 professional young male volleyball players undertook two different RE loading patterns: 1) cluster loading pattern, 2) traditional loading pattern which was standardized for total volume and completed in a randomized crossover fashion with a four-day interval between trials. Blood samples were collected before and after RE for markers of oxidative stress and damage. In response to both the cluster and traditional sets, 8-hydroxy-2-deoxyguanosine (8-OHdG), 4-hydroxy-2-nonenal (4-HNE), and uric acid were significantly elevated post exercise (p likewise, the rate of uric acid excretion was greater for the cluster RE (ES: 1.6 vs. 1.4). These data suggests that RE induced DNA damage, and lipid peroxidation, but they were greater for the traditional RE. Therefore, strength and conditioning professionals in the field of volleyball must keep in their mind that RE induces oxidative stress and should use proper RE loading patterns in their training schedule.
关键词：free radicals; resistance exercise; oxidative damage biomarkers; set configuration
