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  • 标题:Protein Classification By Analysis of confocal Microscopic Images of Single Cells
  • 本地全文:下载
  • 作者:T. Steckling ; O. Hellwich ; S. Wälter
  • 期刊名称:ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
  • 印刷版ISSN:2194-9042
  • 电子版ISSN:2194-9050
  • 出版年度:2004
  • 卷号:XXXV Part B5
  • 页码:302-305
  • 出版社:Copernicus Publications
  • 摘要:Proteins being present in a living cell fulfil a certain task in the cell. As a consequence of its functionality a protein is located in certain parts of the cell. If it is made visible the resulting patterns can help to identify the protein, as the spatial distribution of the visible structures depends on the functionality of the protein inside of the cell and, therefore, characterises the protein. The cells used for the experiments were COS-1 cells typically allowing easy microscopic data takes as the cells are much larger than their nuclei. With the help of a suitable parameterisation the proteins can be automatically identified. In order to derive such a parameterisation, features describing the spatial structure of the protein are extracted. The stochastic behaviour of the features is of major importance for the performance of the method
  • 关键词:image analysis; feature selection; classification; medical image processing; microscopic imagery
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