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  • 标题:Metabolic Adaptations to Arsenic-Induced Oxidative Stress in Hapalosiphon fontinalis-339
  • 本地全文:下载
  • 作者:Sunaina Zutshi ; Fareha Bano ; Khalid Habib
  • 期刊名称:International Journal of Innovative Research in Science, Engineering and Technology
  • 印刷版ISSN:2347-6710
  • 电子版ISSN:2319-8753
  • 出版年度:2014
  • 卷号:3
  • 期号:2
  • 页码:9386
  • 出版社:S&S Publications
  • 摘要:Arsenic is the most common nonessential widely occurring metal with serious hazardous impacts on livingorganism. Arsenic enriched soils are considered major sources of contamination in the food chains and water supplies.Presence of arsenic is of great environmental concern due to its carcinogenic and mutagenic property in addition to hightoxicity. Very little work is done on arsenic induced toxicity and resistance in cyanobacteria who are main producer of aquaticsystem. Thus during present investigation, in vitro study was done to determine the toxic effect of Sodium Arsenate (0-100mM) on an aquatic cyanobacteria Hapalosiphon fontinalis-339 with respect to lipid peroxidation, ion leakage,photosynthetic pigments, antioxidant enzymes and non enzymic oxidative substances. 50% decrease in growth (LC50) wasobserved at 70 mM sodium arsenate. A marked reduction in photosynthetic pigments was observed in test organism atsublethal concentration (100mM sodium arsenate). At this level MDA production was enhanced that probably resulted indecreased growth of the test organism. Accumulation of enzymic and non enzymic substance e.g. superoxide dismutase,catalase, and ascorbate peroxidase activities and proline, total glutathione showed an efficient antioxidative potentialmechanism in Hapalosiphon fontinalis-339.
  • 关键词:Sodium Arsenate pollution; Oxidative stress; Hapalosiphon fontinalis-339; Electrolyte leakage; Antioxidant;defence system.
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