期刊名称：International Journal of Innovative Research in Science, Engineering and Technology
印刷版ISSN：2347-6710
电子版ISSN：2319-8753
出版年度：2014
卷号：3
期号：9
页码：15979
DOI：10.15680/IJIRSET.2014.0309028
出版社：S&S Publications
摘要：Gene expression indicates the present state of the cell. Samples associated with the normal and cancerstomach tissues in Homo sapiens are collected by providing different stomach tissue query terms from GEO andArrayExpress database. Manual curation is carried using Standard Operating Procedure (SOP) for both normal andcancerous condition. These samples are submitted to the novel algorithm developed at IBAB, Bangalore, to validatesamples and identify stomach cancer specific genes. The study retrieved 1336 samples for stomach cancer condition.From 1336 samples it is known that genes expressed in stomach cancer were 12309; genes not expressed in stomachcancer were 7531. The study also retrieved 434 samples for normal stomach condition, by analyzing it is known thatgenes expressed in Normal stomach were 10477 and genes not expressed in Normal stomach were 9327. Bycomparison, 2080 genes were identified which were expressed in stomach cancer and not detected in Normal stomachtissue.
关键词：Gene expression; Meta analysis; stomach cancer; biocuration (manual curation)
