Hyponateremia is a medical condition commonly seen in patient with progressive cirrhosis. The study was conducted on total 30 cirrhotic patients. Group 1 showed mean eGFR (93.9 ± 12 ml/min/1.73m2) by simplified MDRD equation, significantly (p<0.001) above reference value (75 ml/min/1.73m2) as agreed upon, lower normal value as per RIFLE classification. Group 2 showed mean eGFR (48.8 ± 14.7 ml/min/1.73m2) significantly (p<0.001) below the normal reference value.