A study was conducted to determine Gastrointestinal nematode (GIN) egg count in faeces based on McMaster technique (EPG method) in naturally infected cattle around Sylhet Agricultural University. About 60 cattle were selected and divided into three groups of 20 animals each: the 1^st group was treated with albendazole, the 2^nd group was treated with levamisole and the 3^rd with ivermectin. Faecal samples were collected on day 0 before treatment and again day on 12 post treatment. Pre Treatment Mean EPG±SE for albendazole group was 850±18.137, levamisole group was 650±22.064 and ivermectin group was 550±16.623. After post treatment we got Mean EPG±SE for albendazole group was 100±8.885, levamisole group was 50±8.885 and ivermectin group was 200±17.770. After treatment with albendazole, levamisole and ivermectin it reduced EPG count significantly (p<0.001). Further detailed investigations are necessary to clarify the current status in different agro ecology, species of animals and management systems.