摘要：Handajani NS, Dharmawan R. 2009. Effect of VCO to leucocyte differential count,glucose levels and blood creatinine of hyperglycemic and ovalbumin sensitized Musmusculus Balb/c. Nusantara Bioscience 1: 1-10. Chemical medicines and insulin candecrease glucose blood level on hyperglycemic patients with macro vascular sideeffect. Diabetes and allergy incidences are influenced by quality and quantity ofleucocytes. Lauric acid within VCO reports decreased glucose blood level of diabetesand some allergy incidents. The purpose of the study is to know the effect of VCO onglucose blood level, differential leucocytes count and creatinine blood level onhyperglycemic and normoglicemic ovalbumin sensitized mice. Forty five (45) male(mice) of Mus musculus Balb/c with average weight of 35 g are divided into 9 groupswith 5 repetitions, those are 4 non alloxan groups and 5 alloxan inducedhyperglycemic groups. On 22nd day to 36th day they are sensitize to ovalbumin asallergen. Blood sample was obtained by orbital vena using heparin as anti coagulantin order measuring glucose blood level by GOD method to 6 times, on 1st, 4th, 18th,22nd, 32nd and 37th days, then are tested by ANOVA followed by DMRT 0.05. On 37thday, differential leucocytes are determined, blood level are counted, and thencompared to normal value. The result of this study were that within differentialleucocytes count of hyperglycemic mice, neutrophile percentage were much lowerthan the normal value (3.22%), and lymphocyte percentage were much higher thanthe normal value (94.54%). Consumed 0.003 mL/35 g VCO more 18 days decreasedglucose blood level on hyperglycemic mice, decreased basophile percentage ofovalbumin sensitized mice, normalized neutrophile percentage no increasedcreatinine blood level.
