摘要：This study aims todetermine treatment effect of VCO on blood cholesterol levels in hypercholesterolemicwhite rat (Rattus norvegicus L.). This study used 25 male rats of Wistarstrain divided into five treatment groups, namely: control, simvastatin (1.3 mL/270 gBW), cholesterol (9:1 lard), VCO 1 (1 mL/270 g BW), and VCO 2 (1.3 mL/270 g BW).Treatment was given orally. Total cholesterol, LDL and HDL cholesterol levels weremeasured at day 1, day 14 and day 28. Cholesterol data (total cholesterol, LDL andHDL) were analyzed by Ancova and followed by contrast test at significance level of5%.. The results showed that treatment of VCO at different doses significantlyaffected the decrease in blood total cholesterol, blood LDL levels, increasing bloodHDL in hipercholesterolemic white rat.
