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  • 标题:Hepatitis C virus molecular epidemiology in Latvia
  • 本地全文:下载
  • 作者:Juris Jansons ; Gunita Sudmale ; Irina Sominskaya
  • 期刊名称:Environmental and Experimental Biology
  • 印刷版ISSN:1691-8088
  • 出版年度:2004
  • 页码:53-64
  • 出版社:University of Latvia
  • 摘要:The aim of this study was to identify the hepatitis C virus (HCV) genotypes distributed in Latviaand to estimate their prevalence in various risk groups. HCV genotypes of 65 isolates were estimatedusing amplifi cation and direct sequencing of PCR fragments from the core region of HCV genome.Phylogenetic analysis of the genotypes was conducted. Genotype 1b was identifi ed in about 85 % ofcases, genotype 3a in about 10 %, and HCV genotypes 1a and 2c were present only in some isolates.A similar epidemiological distribution is typical for the former Soviet Union Republics. Our studysuggests that contaminated blood products may be main route of HCV infection in Latvia.
  • 关键词:genotypes; HCV; prevalence
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