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  • 标题:Population genetics models for the statistics of DNA samples under different demographic scenarios - Maximum likelihood versus approximate methods
  • 本地全文:下载
  • 作者:Andrzej Polański ; Marek Kimmel
  • 期刊名称:International Journal of Applied Mathematics and Computer Science
  • 电子版ISSN:2083-8492
  • 出版年度:2003
  • 卷号:13
  • 期号:3
  • 出版社:De Gruyter Open
  • 摘要:The paper reviews the basic mathematical methodology of modeling neutral genetic evolution, including the statistics of the Fisher-Wright process, models of mutation and the coalescence method under various demographic scenarios. The basic approach is the use of maximum likelihood techniques. However, due to computational problems, intuitive or approximate methods are also of great importance
  • 关键词:DNA samples; demography; coalescence
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