摘要:Adult acute lymphoblastic leukemia (ALL) is a biologically heterogeneous illness of transformed B- and T-cell pre- cursors. Each subset can be subdivid- ed into several other entities, to consti- tute a wide spectrum of clinico-prog- nostic syndromes (1). In B-ALL, a basic distinction is between Philadelphia (Ph)-chromosome/BCR-ABL-positive and -negative disease, the former sub