期刊名称：International Journal of Innovative Research in Science, Engineering and Technology
印刷版ISSN：2347-6710
电子版ISSN：2319-8753
出版年度：2016
卷号：5
期号：5
页码：8588
DOI：10.15680/IJIRSET.2016.0505251
出版社：S&S Publications
摘要：Non alcoholic fatty liver disorder (NAFLD), as the name suggest is the accumulation of fat content inthe liver due to reasons other than consumption of alcohol. Under NAFLD we can find a range of diseases, NonAlcoholic Steatohepatitis (NASH) being the most prominent one. It is a scenario where the inflammation maybe aresult of response to stress that may lead to accumulation of lipid in the liver.One of the main causes of NAFLD is the deficiency of Vitamin D. Vitamin D can either be obtained exogenously byexposure to sunlight or endogenously by diet metabolism in the liver. Recent studies provides evidence that even whenexposed to adequate sunlight, the amount of Vitamin D acquired has not been able to meet the requirement of the body,without supplementation. Low Vitamin D levels are associated with high prevalence of NAFLD. Its deficiency andinsufficiency has led to a systemic increase in inflammation. The precise role of Vitamin D in NAFLD is notcompletely known but its association with innate and adaptive immunity and its anti proliferative effect explains itssignificance in such diseases.
