期刊名称：International Journal of Innovative Research in Science, Engineering and Technology
印刷版ISSN：2347-6710
电子版ISSN：2319-8753
出版年度：2013
卷号：2
期号：9
页码：4467
出版社：S&S Publications
摘要：The cell envelope of Mycobacterium tuberculosis (Mtb) is composed of a matrix of peptidoglycan, mycolicacids, lipids, and carbohydrates along with some proteins. The characterization of proteins associated with the cell wallis presently needed to understand the bacteria in terms of its survival, immune modulation in the host, resistant to drugsetc ,so as to find a way to combat tuberculosis disease. In this study, a cell wall hypothetical protein Rv2004c was takenfor further characterization and functional annotation using various Bioinformatics tools like FASTA, STRING,InterproScan etc. Also insilico modeling of this protein was carried out with Robetta, an automated modeling tool andSAVS, a validation server and finally a valid model was obtained.
