摘要：The aim of the present study was to evaluate antioxidant activity of secondary metabolites of Streptomyces species isolated frommarine soil sample collected from the Bay of Bengal coast of Puducherry, India. The sample was serially diluted and plated onStarch casein agar and actinomycetes were selectively isolated. The broth culture of the International Streptomyces Project-1 (ISP-1)medium was used for fermentation process and extracellular metabolites were extracted using the solvent ethyl acetate. The browncolored extract obtained was dissolved in DMSO and screened for DPPH radical scavenging activity. The secondary metaboliteshowed 83% inhibition at 0.2mg/ ml, and the inhibition was compared with the standard antioxidant ascorbic acid which showed84% inhibition at 0.2mg/ ml concentration. The potential strain ABTRI12 was identified as Streptomyces species and designated asStreptomyces sp. ABTRI12. However, most antimicrobial activity was found in the genus Streptomyces isolates. The partialcharacterization of the crude extracts by IR spectra analysis revealed the possible presence of terpenoid, long chain fatty acids andsecondary amine derivatives compounds in the extracts. The findings of the present study suggested that the marine isolateStreptomyces sp. ABTRI12 could be a potential natural source of antioxidants.
关键词：Marine actinomycetes; Antioxidant; Antimicrobial; IR spectrum; Puducherry
