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文章基本信息

  • 标题:An invariant allocation function for multi-treatment clinical trials
  • 作者:Uttam Bandyopadhyay ; Rahul Bhattacharya
  • 期刊名称:Statistics and Its Interface
  • 印刷版ISSN:1938-7989
  • 电子版ISSN:1938-7997
  • 出版年度:2016
  • 卷号:9
  • 期号:1
  • 页码:1-10
  • DOI:10.4310/SII.2016.v9.n1.a1
  • 出版社:International Press
  • 摘要:An allocation function, invariant under monotonic transformation, is proposed in the context of multi-arm clinical trials for a class of continuous response distributions. The aim is to skew the allocation towards the most promising treatment using the whole information about the response distributions. A response adaptive implementation based on the proposed allocation function is suggested and assessed through some useful performance measures.
  • 关键词:response adaptive allocation; clinical trial; censoring
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