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  • 标题:Prolactin is a Novel Biochemical Marker in Sera of Iraqi Type-2 Diabetic Women With Metabolic Syndrome in Baghdad.
  • 本地全文:下载
  • 作者:Lamia Shakir Ashoor ; Rasha Zuhair Jasim ; Bushra Hameed Ali
  • 期刊名称:Journal of Natural Sciences Research
  • 印刷版ISSN:2225-0921
  • 电子版ISSN:2225-0921
  • 出版年度:2015
  • 卷号:5
  • 期号:16
  • 页码:129-136
  • 语种:English
  • 出版社:The International Institute for Science, Technology and Education (IISTE)
  • 摘要:Metabolic syndrome (MS) is a group of clinical and biological abnormalities included risk of insulin resistance , disorders in glucose metabolism , abdominal obesity and abnormal lipid profile these features confer a greater risk of cardiovascular diseases . Anyway, the co-occurrence of diabetes mellitus and metabolic syndrome potentiates the cardiovascular risk associated with each of the two conditions. The present study aimed to determine a relationship between prolactin level in type -2- diabetic Iraqi women and metabolic syndrome, as well to find a relationship between prolactin level and other studied biochemical markers. seventy menopausal diabetic women with metabolic syndrome with age in range (45-50) years were enrolled in this study , and were compared with matched age control group which consisted of menopausal women suffering from uncomplicated diabetic patients (without metabolic syndrome ). Two groups were not given any treatment , they were newly diagnosed. This study highlights the role of metabolic syndrome in the abnormalities of prolactin blood glucose , lipid profile , glycated hemoglobin and body mass index regardless the role of diabetic mellitus. Available evidence from the present study have reported that prolactin is a novel biochemical marker in sera of Iraqi menopausal type-2 diabetic women with metabolic syndrome . Moreover this study is the first highlights not only the association between lower level prolactin and metabolic syndrome in type-2 diabetic women but also the correlation between lower prolactin level and other biochemical markers ( Lipid profile , HbA 1c and BMI ) in type-2- diabetic women with metabolic syndrome .
  • 关键词:Prolactin . metabolic syndrome . type-2- diabetes mellitus . lipid prolile
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